A novel chondroprotective property of TSG-6 has therapeutic potential for OA
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چکیده
منابع مشابه
Garlic: a review of potential therapeutic effects
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متن کاملThe inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers.
Tumor necrosis factor-stimulated gene-6 (TSG-6) is a hyaluronan (HA)-binding protein that plays important roles in inflammation and ovulation. TSG-6-mediated cross-linking of HA has been proposed as a functional mechanism (e.g. for regulating leukocyte adhesion), but direct evidence for cross-linking is lacking, and we know very little about its impact on HA ultrastructure. Here we used films o...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2016
ISSN: 1063-4584
DOI: 10.1016/j.joca.2016.01.064